Season
Episode
- Episode 1: Neil Patrick Harris / Karen Fisher / Nickel Creek
- Episode 2: Bruce Campbell / Melinda Clarke / Flight of the Conchords
- Episode 3: Patricia Arquette / Connie Schultz / Paul Weller
- Episode 4: Carla Gugino / Alice Cooper
- Episode 5: Alyson Hannigan / Steve Jones
- Episode 6: Cybill Shepherd / Phil Keoghan / Institute
- Episode 7: Tyra Banks / Tyler James Williams / Ted Alexandro
- Episode 8: Nick Cannon / Jeff Probst / Lawrence Turman
- Episode 9: Aisha Tyler / Seth MacFarlane / Thirty Seconds to Mars
- Episode 10: Susan Sarandon / Tom Everett Scott / INXS
- Episode 11: Danny Bonaduce / Diane Farr / Shaggy
- Episode 12: Maria Bello / Jason Segel
- Episode 13: Alan Alda / Jennifer Coolidge
- Episode 14: Fran Drescher / Robert David Hall / Jo Dee Messina
- Episode 15: Toni Collette / Dave Price / Robert Plant & Strange Sensation
- Episode 16: Julian McMahon / Jennifer Finnigan
- Episode 17: Taryn Manning / Dr. Drew / Butch Bradley
- Episode 18: David Duchovny / Sinéad O'Connor
- Episode 19: Henry Winkler / Aron Ralston / Julie Gribble
- Episode 20: Illeana Douglas / Macy Gray
- Episode 21: Macy Gray / Nuala O'Faolain / Rihanna
- Episode 22: Dennis Hopper / Cheryl Hines / Sarge
- Episode 23: Joe Mantegna / Sue Johanson
- Episode 24: Sanjay Gupta / Stephen Collins
- Episode 25: Bill Nye / Kevin Bacon & Michael Bacon / Bacon Brothers
- Episode 26: Joely Fisher / McG / Switchfoot
- Episode 27: Melina Kanakaredes / Stephen Robinson
- Episode 28: Betty White / Rhona Mitra / Ray J
- Episode 29: Stockard Channing / Michael Connelly / Jamie Cullum
- Episode 30: Jason Schwartzman / Mitch Braswell / Paul Weller
- Episode 31: Sharon Osbourne
- Episode 32: Maria Bartiromo / Jamie Kaler / Clint Black
- Episode 33: Anthony LaPaglia / Jeri Ryan
- Episode 34: Charlie Sheen / Marissa Jaret Winokur / Franz Ferdinand
- Episode 35: Gina Gershon / Rob Zombie / Sinéad O'Connor
- Episode 36: Hugh Laurie / Twiggy / Patty Loveless
- Episode 37: Brenda Blethyn / Jim Sheridan / John Roy
- Episode 38: John Leguizamo / Kara Cooney / My Morning Jacket
- Episode 39: John Malkovich
- Episode 40: Xzibit / Doug Savant / Buddy Guy
- Episode 41: James Belushi / Parminder Nagra / Matisyahu
- Episode 42: Patti Smith / John Lahr
- Episode 43: Anne Heche / Tom Amandes / Jay Larson
- Episode 44: RZA / Josh Schwartz / Amos Lee
- Episode 45: Jon Favreau / Randy Cohen / Maz Jobrani
- Episode 46: Juliette Lewis / Brian Van Holt
- Episode 47: Jerry O'Connell / Joely Richardson / The Fray
- Episode 48: Regis Philbin / Maureen Dowd
- Episode 49: Jennifer Love Hewitt / James Denton / Robert Plant
- Episode 50: Danny Bonaduce / Paul Haggis
- Episode 51: Ted Danson / Kristen Bell / Matt Fulchiron
- Episode 52: Sela Ward / Lawrence O'Donnell / Chris Botti / Paul Buchanan
- Episode 53: Tony Shalhoub / Mitch Albom
- Episode 54: Miranda Lambert / Malachy McCourt
- Episode 55: Tom Arnold / Helen Fielding / Lifehouse
- Episode 56: Jon Cryer / Amy Yasbeck
- Episode 57: John Waters / David Steinberg / Nada Surf
- Episode 58: Poppy Montgomery / Mancow
- Episode 59: Michelle Yeoh / Jeremy Roenick / Trey Anastasio
- Episode 60: Chris Isaak / Sara Gilbert / Keaton Simons
- Episode 61: Dennis Quaid / Bill Nye / Bob Marley
- Episode 62: Dwight Yoakam / Teri Garr
- Episode 63: Little Richard / Brian Cox
- Episode 64: Téa Leoni / Amy Tan / RZA
- Episode 65: Katey Sagal / Colin Hanks / Brian McKnight
- Episode 66: Drew Pinsky / Bob Spitz
- Episode 67: Fred Willard / Connie Schultz
- Episode 68: Rob Morrow / Bob Marley
- Episode 69: Don Rickles / Ivana Miličević / Aimee Mann
- Episode 70: Daryl Hannah / Thomas Lennon
- Episode 71: Cheryl Hines / Derek Luke / Trey Anastasio
- Episode 72: Phil McGraw / Sebastian Maniscalco
- Episode 73: Seth Green / Peter Bart / Peter Guber
- Episode 74: Tom Selleck / Connie Britton / Ian Edwards
- Episode 75: Steven Wright / Lola Glaudini / Anthony Hamilton
- Episode 76: Allison Janney / John C. McGinley / The 88
- Episode 77: Greg Kinnear / Paula Poundstone / Ming Tsai
- Episode 78: Thomas Cavanagh
- Episode 79: Vanessa Williams / Rogue Wave
- Episode 80: Mimi Rogers / Living Things
- Episode 81: Drew Pinsky / Amy Yasbeck / Wicked Tinkers
- Episode 82: Jim Belushi / Parminder Nagra / Matisyahu
- Episode 83: James Woods / Piper Perabo / Keaton Simons
- Episode 84: Emma Thompson / Steve Byrne
- Episode 85: Lynn Redgrave / Isaiah Washington / Mutemath
- Episode 86: Mary Steenburgen / Big & Rich
- Episode 87: Jeff Probst / Lauren Holly / Ne-Yo
- Episode 88: Zooey Deschanel / Trace Adkins
- Episode 89: Jean Reno / Sanaa Lathan
- Episode 90: Eddie Izzard / Patti Hall
- Episode 91: Alyson Hannigan / Paul Haggis / Frank Caliendo
- Episode 92: Marlee Matlin / Lisa Loeb
- Episode 93: Paul Reiser / Judy Greer / Jeff Cesario
- Episode 94: Kiefer Sutherland / Amy Adams / Rocco DeLuca and the Burden
- Episode 95: Jason Biggs / Fiona Apple
- Episode 96: William Shatner / Josh Bernstein / Andrea Bocelli
- Episode 97: Carl Reiner / Nadine Velazquez / Robert Hawkins
- Episode 98: Carl Edwards / William H. Macy
- Episode 99: Samuel L. Jackson / Cokie Roberts / The Lashes
- Episode 100: Dolly Parton / Kevin Smith / The Cult
- Episode 101: Terrence Howard / Eric Haney
- Episode 102: Regis Philbin / Tichina Arnold / Jenny Lewis & the Watson Twins
- Episode 103: Roseanne Barr / Wolfgang Puck
- Episode 104: Kathy Bates / Idina Menzel / Jeremy Bloom
- Episode 105: Milla Jovovich / Peter Travers / All American Rejects
- Episode 106: Paul Haggis / Ben Lee / James Blake
- Episode 107: Tyra Banks / Jackie Collins / Nathan Sawaya
- Episode 108: John Larroquette / Ethan Suplee / Fiona Apple
- Episode 109: Wynonna / Emilie de Ravin / D. C. Benny
- Episode 110: David Arquette / Cowboy Troy
- Episode 111: Stockard Channing / Big & Rich
- Episode 112: Rosanne Cash / Howie Mandel
- Episode 113: Jason Lee / Julian Sands / David Gray
- Episode 114: Joan Cusack / Mary McCormack / The New Cars
- Episode 115: Jane Kaczmarek / Tom Fontana / Dan Naturman
- Episode 116: John Goodman / Angela Nissel / Alkaline Trio
- Episode 117: Frankie Muniz / Annie Duke
- Episode 118: Chris Kattan / Mo'Nique / Ozomatli
- Episode 119: Mehcad Brooks / Anjelica Huston / Ne-Yo
- Episode 120: Rosie O'Donnell / Harry Shearer
- Episode 121: Paget Brewster / Sam Elliott / Adam Ferrara
- Episode 122: Ben Kingsley / Roselyn Sánchez / UB40
- Episode 123: Kevin Pollak / Mira Sorvino / Train
- Episode 124: Christian Finnegan / Chi McBride / Bebe Neuwirth
- Episode 125: Carrie Fisher / John Corbett
- Episode 126: Carl Hiaasen / Toby Keith
- Episode 127: Roger Lay Jr. / Ray Romano / Ken Shamrock
- Episode 128: Melina Kanakaredes / Kyle MacLachlan / Shinedown
- Episode 129: Dennis Quaid / The Wiggles
- Episode 130: Radha Mitchell / Marion Ross / Erin Boheme
- Episode 131: Jennifer Finnigan / Barry Sonnenfeld
- Episode 132: Dave Barry / Dem Franchize Boyz
- Episode 133: Kristin Chenoweth / Andy García / Mandy Moore / Rock Bottom Remainders
- Episode 134: Neil Patrick Harris / Parminder Nagra / The BellRays
- Episode 135: Randy Jackson / Connie Schultz
- Episode 136: Reggie Bush / Jennifer Love Hewitt / Frank McCourt / Secret Machines
- Episode 137: Emily Deschanel / Kelsey Grammer / Aisha Tyler / The Go! Team
- Episode 138: Julia Louis-Dreyfus / Ying-Yang Twins
- Episode 139: Denis Leary / Bo Bice
- Episode 140: Donald Faison / Betty White / Bill Bailey
- Episode 141: Bill Carter / Jenna Fischer / Chris Isaak
- Episode 142: Paul Bettany / Kate Walsh / Damian Marley
- Episode 143: Jacinda Barrett / Mark Harmon / Rock Kills Kid
- Episode 144: Daryl Hannah / Sara Ramirez
- Episode 145: Phil McGraw / Jim Gaffigan
- Episode 146: Merv Griffin / Rick Reilly
- Episode 147: Diane Farr / Dominic Monaghan / Phil Vassar
- Episode 148: Mía Maestro / Nick Lachey
- Episode 149: Reba McEntire / Cynthia Watros / Toby Keith
- Episode 150: Anna Paquin / Casper Van Dien / Jason Aldean
- Episode 151: Ricki Lake / Oscar De La Hoya / The Wreckers
- Episode 152: Pauley Perrette / Brooks and Dunn
- Episode 153: Jenny McCarthy / Jim Short / Gomez
- Episode 154: Jon Favreau / Shooter Jennings / Lee Child
- Episode 155: Patricia Heaton / Claire Fordham / The New Cars
- Episode 156: Ian McShane / Joey Lauren Adams / Stanley Bing
- Episode 157: Edie Falco / David Lee Roth
- Episode 158: Tom Everett Scott / Ludacris / Speech
- Episode 159: Sara Rue / Anthony Michael Hall / Secret Machines
- Episode 160: Anderson Cooper / Mercedes Ruehl / Dan Cummins
- Episode 161: Lorraine Bracco / Kevin Connolly / Jamie Jenson
- Episode 162: Tony Shalhoub / Lucy Davis / Echo & the Bunnymen
- Episode 163: Jon Cryer / Jim Short / Three Days Grace
- Episode 164: Pepe the King Prawn / Sarah Wynter / The Charlatans
- Episode 165: Katey Sagal / David Milch / Arturo Gatti
- Episode 166: Stanley Tucci / Cat Deeley / Van Hunt
- Episode 167: Jack Black / James Marsden / Sonya Kitchell
- Episode 168: Tyrese Gibson / Def Leppard / Paul Morrissey
- Episode 169: Regis Philbin / John Landis / Snoop Dogg
- Episode 170: Henry Winkler / Judy Greer / Mike Young
- Episode 171: Dave Foley / Amy Sedaris / UB40
- Episode 172: Tim Robbins / T.I.
- Episode 173: Jesse James / Paul Dinello / She Wants Revenge
- Episode 174: Laurence Fishburne / Illeana Douglas, / Jack's Mannequin
- Episode 175: Tom Lennon / Jewel
- Episode 176: Donal Logue / Ne-Yo
- Episode 177: Toni Collette / Lawrence Block / Joe Theismann
- Episode 178: Julie Chen / Denise Mina / Echo & the Bunnymen
- Episode 179: Danny Bonaduce / Cote De Pablo / Bill McArthur
- Episode 180: Joe Mantegna / Brooks & Dunn
- Episode 181: Nick Cannon / Kyle Dunnigan / Family Force 5
- Episode 182: Eddie Izzard / Greg Warren / The Buzzcocks
- Episode 183: Kevin Smith / Carrie Ann Inaba / Seether
- Episode 184: Cuba Gooding Jr. / Jay Larson / Jurassic 5
- Episode 185: Greg Kinnear / Hugh Hefner / Sammy Hagar
- Episode 186: Kyra Sedgwick / Keith Olbermann
- Episode 187: Andie MacDowell / Cirque du Soleil's KA
- Episode 188: Bonnie Raitt / Travis Pastrana / Randy Kagan
- Episode 189: Drew Pinsky / Carnie Wilson / Tally Hall
- Episode 190: Jaime Pressly / Robbie Coltrane / Michael Franti & Spearhead
- Episode 191: Carlos Mencia / Natasha Bedingfield
- Episode 192: Steve Carell / The Subways
- Episode 193: Aaron Eckhart / Cheyenne Kimball / Fran Solomita
- Episode 194: Tim Olyphant / Lindsay Sloane / The Editors
- Episode 195: Christina Milian / Tim Olyphant / Brian Malow
- Episode 196: Michael Clarke Duncan / Laura Kightlinger / Rob Zombie
- Episode 197: Chi McBride / Lili Taylor / Nick Lachey
- Episode 198: Matt Dillon / Padma Lakshmi / Paula DeAnda / Baby BashMatt Dillon / Padma Lakshmi / Paula DeAnda / Baby Bash
- Episode 199: Alice Cooper / Penelope Ann Miller
- Episode 200: Jane Kaczmarek / Esai Morales / Larke Miller
- Episode 201: Shannen Doherty / Eddie Kaye Thomas / E-40 T-Pain
- Episode 202: Fred Willard / Rachel Blanchard / Stephen J. Cannell
- Episode 203: Amy Smart / Trace Adkins
- Episode 204: Denis Leary / Lewis Dix / Matt Goss
- Episode 205: André Benjamin / David Boreanaz / Mellowdrone
The Late Late Show with Craig Ferguson - Season 2 Episode 2 : Bruce Campbell / Melinda Clarke / Flight of the Conchords
Shannen Doherty; Eddie Kaye Thomas; E-40; T-Pain.
